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In the early breast cancer clinical trial, the most common side effects reported with arimidex include hot flashes, joint symptoms including arthritis and arthralgia , weakness, mood changes, pain, back pain, sore throat, nausea, vomiting, rash, depression, high blood pressure, osteoporosis, fractures, swelling of the arms and legs, insomnia difficulty sleeping , and headache.

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Those suffering from osteoporosis or at risk of it can not take arimidex anastrozole .

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Arimidex interferes with natural processes in the body, which may cause common side effects such as weakness, hot flashes, numbness or tingling, swelling in ankles or feet, joint pain, stiffness, problems gripping, back pain, bone pain, depression, mood changes, insomnia, high blood pressure, sore throat, headache, nausea, vomiting, or mild rash.

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The sample size was revised again when 68-month outcomes in the arimidex, tamoxifen, alone or in combination atac trial 18 showed an estimated 5-year efs rate on anastrozole of 86.

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in multiple daily dosing trials with 5 and 10 mg, thyroid stimulating hormone tsh was measured; there was no increase in tsh during the administration of arimidex.

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